Myxedema

Myxedema

is an endocrine disease that is associated with a situation where organs and tissues can not be fully provided with thyroid hormones. Myxedema is in fact an extreme form of hypothyroidism (acquired) in adults (in children the extreme form of hypothyroidism (can be congenital) is called cretinism).

Hypothyroidism is a state of the body (hypothyroidism is not a disease as such), when there is a prolonged lack of thyroid secretion products in it. Hypothyroidism is caused either by functional deficiency of the thyroid tissue when it is not capable of producing the required number of hormones) or with certain pathological processes that to some extent influence hormonal metabolism. One of the reasons for the development of myxedema is associated with inflammatory processes in the thyroid gland.

The cause of myxedema is inflammatory thyroid disease.

Inaccurate statement. Not only inflammatory, but also tumor, as well as autoimmune lesions of this organ. In addition, this disease can be caused by the introduction of radioactive iodine, with the hypothalamic-pituitary system functioning incorrectly. Myxedema can occur as a result of operations performed on the thyroid gland.

Drowsiness is one of the symptoms of myxedema.

The patient may also have pale and dry skin. There may be signs of puffiness on the limbs and face (there is swelling of the skin and subcutaneous tissue). The hair of the patient becomes brittle, their loss is noted. A frequent phenomenon with myxedema is lowering blood pressure and slowing the pulse. Children often suffer from a decrease in mental abilities in the case of myxedema. There are often less serious neuropsychic disorders. These include, for example, a bad mood. As a result of the disease myxedema can be observed memory impairment. With regard to thyroid hormones, the data of laboratory studies show a decrease in their number in serum.

Myxedema is divided into several types.

There are usually two types of this disease. The first kind is a thyroid miksedema, which can be as innate. And acquired. Congenital myxedema appears as a result of intrauterine infection of the fetus or the presence of vices. Acquired myxedema develops as a result of getting injuries of the thyroid gland or as a result of some transferred diseases. Hypothalamic-pituitary myxedema is a consequence of the abnormal functioning of the hypothalamic-pituitary system. In particular, this concerns the violation of the synthesis of thyroid-stimulating hormone.

Primary hypothyroidism is more common in women.

This is indeed so. For hypothyroidism, drowsiness, memory loss, slowness are characteristic. A person quickly gets tired (even after a minor work done), his performance is also reduced. The voice becomes hoarse. The body temperature is lowered. It should be understood that a person with primary hypothyroidism (which is provoked by an autoimmune lesion) may have primary insufficiency of other peripheral endocrine glands. These are adrenal glands, pancreas, parathyroid glands.

Substitution therapy is the basis for treating myxedema.

Substitution therapy is prescribed for life and includes the use of thyroid medications. These are thyroxine, thyroidin, triiodothyronine, and also combined preparations. These include thyrotoxicum, thyrotome forte, thyrecombe.

The term “myxedema” has been used since the nineteenth century.

In 1878 he named VM Ord a condition of mucous edema of the skin and subcutaneous tissue. However, at present the concept of “myxedema” is used to determine severe forms of hypothyroidism. Although, as is known, mucous edema is characteristic of hypothyroidism.

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